Maurizio Pellecchia

Company: University of California Riverside & Armida Labs

Job title: Professor of Biomedical Sciences, Director Center for Molecular & Translational Medicine

Seminars:

Targeting of Histidine Residues to Increase the Pool of Potential Targets Amendable for Covalent Drug Discovery 3:00 pm

Showcasing how to identify and map histidine residues across a wide range of proteins to determine their potential as covalent drug targets How to marry the right electrophiles with histidine moieties Ligand-first versus electrophile-first approaches to target Histidine residues Read more

day: Conference Day One

Panel Discussion: Debating Systematic & Scalable Screening Methods to Rationally Discover & Develop Covalent Handles with Optimized Reactivity & Selectivity 10:00 am

Debating the pros and cons of target-agnostic and target-focused screening to identify the best use cases What are the best methods for finding tractable hits? Discussing how to balance reactivity with sensitivity within screening cascades Streamlining hit to lead by sifting through hits and appropriately triagingRead more

day: Conference Day One