Lynn McGregor

Company: Novartis AG

Job title: Senior Principal Scientist

Seminars:

Roundtable Discussion: Fueling the Covalency Renaissance by Strategizing the Chemistry Toolbox to Target Residues Beyond Cysteine with Orthogonal Reactivity 4:30 pm

Which amino acids are seen as the next frontier in covalent drug discovery? What is the mass spectrometry or alternative screening toolbox for other amino acids? How can we build drug-like warheads that hit other sidechains? Should we be screening these more promiscuous warheads? What are the different methods to validate non-cysteine covalency in simplified…Read more

day: Conference Day One

Covalency Offers Unique Opportunities for Difficult Targets 9:00 am

Covalency provides opportunities for difficult drug targets Screening identifies a starting point for a TF target Proteomics is an essential tool for covalency focused efforts Read more

day: Conference Day One