Profiling Approved Covalent Drugs to Guide Multiparameter Optimization of Covalent Drug Candidates
Time: 9:00 am
day: Conference Day Two
Details:
- Evaluating intrinsic reactivity and in vitro metabolism for representative approved covalent drugs
- Chemoproteomic profiling to gain insights into covalent binding burden and proteome-wide selectivity
- Considerations for optimization of covalent drug candidates based on approved covalent drug profiles
