Panel Discussion: How Can We Build Covalent Chemistries that Drive Selectivity & Open New Unvalidated Target Spaces such as Non-Cysteine Residues
Time: 11:15 am
day: Conference Day Two
Details:
- What are some example novel warheads that are being explored to advance covalent modification to new acid residues?
- How can we effectively target “soft” nucleophiles that are not as reactive as cysteine?
- Are there unvalidated target spaces that have not yet been drugged which covalency can open up? Such as through nonsmall molecule drugs or by going after non-peptide targets?
