Lessons Learned from Developing Covalent Inhibitors & Covalent PROTACs
Time: 11:45 am
day: Conference Day Two
Details:
- Applying chemoproteomics to characterize covalent inhibitor reactivity in the proteome
- Developing a covalent BTK PROTAC with single digit nM DC50
- Elucidating the ternary complex structure of the covalent BTK PROTAC
