Leaving a Permanent Mark: Harnessing Covalent Chemoproteomics to Target Native Proteoforms
Time: 9:00 am
day: Conference Day One
Details:
- Identifying and targeting reactive protein sites in their natural context to modify protein localization and function
- Condensing reactive warheads against relevant protein sites into a comprehensive library of fragments and lead-like compounds to maximize clinically relevant hits
- Creating automated workflows integrating mass spectrometry, protein analysis and algorithmic learning to accelerate covalent drug discovery
