Structure-free, Site-resolved Contrastive Learning to Empower Rapid Covalent Ligand Discovery

• Development of an AI model to predict and localize covalent ligand binding without folding proteins
• In silico discovery of cryptic pockets and novel binding sites to exploit in drug design
• Profiling covalent ligands on a unique chemoproteomics platform provides site-resolved training data to power this model

Speakers:

William Fondrie

Head of Data Science & Engineering

Talus Bio