William Fondrie
Head of Data Science & Engineering Talus Bio
Seminars
Wednesday 21st October 2026
Structure-free, Site-resolved Contrastive Learning to Empower Rapid Covalent Ligand Discovery
9:00 am
- Development of an AI model to predict and localize covalent ligand binding without folding proteins
- In silico discovery of cryptic pockets and novel binding sites to exploit in drug design
- Profiling covalent ligands on a unique chemoproteomics platform provides site-resolved training data to power this model
