Stephan Hacker
Assistant Professor Leiden University
Seminars
Wednesday 21st October 2026
Expanding the Covalent Toolbox: Profiling Electrophile Selectivity to Enable Next-Generation Warhead Discovery
2:30 pm
- Profiling proteome-wide amino acid selectivity of electrophiles using unbiased mass spectrometry-based approaches
- Exploring electrophiles targeting amino acids other than cysteine as a novel strategy for expanding covalent drug discovery applications
- Developing diverse electrophile libraries and direct-to-biology workflows to identify covalent binders
