Petr Jansa
Vice President, Head of Chemistry BridGene Biosciences Inc.
Seminars
Thursday 22nd October 2026
Proteome-Wide Live-Cell Covalent Screening Reveals Physicochemical Drivers of Promiscuous Labeling & Design Principles for Selective Covalent Libraries
9:30 am
- Introducing the IMTAC TM proteome-wide cell-based screening platform
- Interrogating proteome-wide screening data to characterize compound reactivity and uncover patterns that contribute to selectivity or promiscuity of covalent compounds
- Refining covalent library design strategies to minimize promiscuity and eliminate nonproductive compounds, enabling more efficient, higher-quality hit identification
