Jaimeen Majmudar
Head Research Fellow, Chemical Biology Pfizer
Jaimeen Majmudar, Ph.D. is an Associate Research Fellow at Pfizer. He obtained his Ph.D. at Purdue University and was the American Heart Associate Postdoctoral Fellow at the University of Michigan. He specializes in Chemical Biology approaches to determine small molecule function in cells. He has a deep background in synthetic organic medicinal chemistry and chemical biology, focusing on quantitative chemo-proteomics, target identification, and chemical probe design.
Seminars
Thursday 22nd October 2026
Actionable Decisions & Strategic Risk in Covalent Drug Discovery
9:00 am
- Interrogating covalent and reversible-covalent hits in the absence of a clear hypothesis to identify the truly functional system and define allosteric modulation strategies
- Uncovering mechanism beyond inhibition by revealing PPI disruption as the primary driver of efficacy through target engagement and mass spec validation
- Applying context dependent reversibility and chemical risk assessments to make decisive go/no go calls, advancing one program through preclinical safety while strategically discontinuing another
