Claire Metrick
Senior Scientist, Structural Biology Takeda Pharmaceutical
Seminars
Wednesday 21st October 2026
Roundtable Discussion: Harnessing Covalent Induced Proximity to Expand Druggable Space
12:00 pm
- How does shifting from traditional occupancy-driven covalent inhibition to induced proximity strategies redefine pharmacology and target selection?
- How can distal or previously non-functional nucleophilic residues be effectively leveraged through covalent induced proximity to expand the utility of covalent fragments?
- What are the key opportunities and challenges in designing covalent induced proximity systems (e.g., PROTACs, molecular glues) to unlock new therapeutic mechanisms beyond inhibition?
Wednesday 21st October 2026
Chair’s Opening Remarks
8:50 am
Wednesday 21st October 2026
Chair’s Closing Remarks
5:00 pm
