RAPID – Photoaffinity-Based High-Throughput Ligand Discovery in Cells

  • Pivoting away from mass spec in favor of building a high-throughput chemotherapeutics hit identification platform
  • Discovery of first-in-class inhibitors of a genetically validated target for the treatment of PKU Discovery of the first inhibitors for transcription factor IRF3
  • Evolving the platform to work with other covalent warheads